Why Federal Support is Critical for the Future of SNP Testing in Forensics
Massively parallel sequencing and SNP testing is the future of forensics, but federal support is necessary if we are to bring this future to everyone and their families.
David Mittelman
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Measuring Close and Distant Genetic Relationships
From early methods like blood group analysis to modern approaches using massively parallel sequencing, scientists have developed quantitative techniques to measure genetic relationships.
What’s in a Label? Understanding Biogeographical Ancestry
Every detail matters and any detail could be a clue so when you use advanced DNA tools such as biogeographical ancestry analysis, you should expect, and in fact demand, a complete genomic analysis, without shortcuts.
Refining Genetic Connections in MDFI using the Segment Comparison and Triangulation Tools
The new MDFI Triangulation tool helps confirm that shared DNA segments between three or more individuals are inherited from a common ancestor, providing stronger evidence of true genetic relationships.
Implementing Forensic Sequencing: Microarrays, Massively Parallel Sequencing, and Call Rate
Call rate is an indicator of data quality for microarrays but doesn't mean much for DNA sequencing, and since microarrays are wrong for forensics samples, we need to move past call rates and agree on better quality metrics.
Dense SNP-based analyses complement forensic anthropology biogeographical ancestry assessments
Comparisons between anthropological and genomic ancestry assignments for UHRs reveals significant discordance, shedding light on the challenges in determining population affinity, particularly for admixed populations.