Measuring Close and Distant Genetic Relationships
From early methods like blood group analysis to modern approaches using massively parallel sequencing, scientists have developed quantitative techniques to measure genetic relationships.
Insights11
Check out the latest posts
What’s in a Label? Understanding Biogeographical Ancestry
Every detail matters and any detail could be a clue so when you use advanced DNA tools such as biogeographical ancestry analysis, you should expect, and in fact demand, a complete genomic analysis, without shortcuts.
Implementing Forensic Sequencing: Microarrays, Massively Parallel Sequencing, and Call Rate
Call rate is an indicator of data quality for microarrays but doesn't mean much for DNA sequencing, and since microarrays are wrong for forensics samples, we need to move past call rates and agree on better quality metrics.
Implementing Forensic Sequencing: Stop Using Degradation Index for Massively Parallel Sequencing
Degradation index is useful for STR typing but irrelevant for SNP testing, especially with modern DNA sequencing, since SNPs can be measured from much shorter DNA fragments than STRs.
Implementing Forensic Sequencing: Are Q scores important for forensic genetic genealogy?
Q scores are an important measure of DNA sequencing accuracy, but in forensic genetic genealogy, sequencing depth and other metrics are more critical for accurately detecting SNPs and building ultra-sensitive DNA profiles.